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Rotarod Apparatus:

Dimensions/Features

NEW Touchscreen User Interface

The new touchscreen graphic user interface allows clear visualization of timing and speed for each lane.

Mechanical detection of fall

Individual lane timers

Electronic rod speed adjustment: constant

speed and fixed acceleration rate

Automatic recording of latencies to fall and rotation speed

Mice and rats combined Rotarod available(Optional)

Advanced ROTAROD solution for big rat (>500 grams)

Specifications:

Number of Animals: 4 Rats/Mouse Rotation Range: 3-80 RPM

Acceleration Rate: 30 seconds to 10minutes with 1 sec increments

Change modes, adjust speed, and create protocols right from the main screen for greater flexibility with maximum functionality and usability

Physical Dimensions:

Base Unit Dimensions mm (inch) (W x D x H) 362x240x375

Total Height mm (inch): 400

Fall Height mm :220

Lane Width mm :50-75

Drum Diameter mm :250

Rod Diameter mm :30-60

Rotarod Apparatus used in Eeuropharmacological Disease

Rotarod Apparatus used in Eeuropharmacological Disease , also known as the rotarod test, is used as a basic assessment tool for coordination and balance in rodents. it provide measure of loco motor ability and Additional behavioral tests that assess loco motor ability, include the open field assessment. the balance beam, the hanging grip test, the vertical pole test, and walking pattern analysis. In its most basic form, the rotarod is comprised of a rotating cylinder upon which an animal is placed. As the cylinder rotates, the animal must move forward to keep from falling off the cylinder. Animals with deficits affecting balance or fall from the apparatus more quicker than animals with normal motor function. The rotarod has proposed as one of a number of behavioral tests for phenotyping genetically modified mice.

Variations on the rotarod:

The cylinder is typically made of a solid such as rubber. The cylinder may be modified with using stainless steel bars as the walking surface.With such modifications, animals may be able to cling to, and rotate with, the rod. When this occurs, after one or two complete rotations, the test is considered complete, and the time recorded. Inbred strains of mice may perform differently on the test . For strains that perform poorly on introduction to the rotarod, it may be beneficial to acclimate the animals to the apparatus prior to beginning the study. Animals with experimentally induced lesions to the CNS and animals receiving therapeutic and experimental compounds may also be tested for motor deficits using the rotarod. animals should be allowed to recover from surgery for a minimum of twenty four hours prior to testing. Drugs and experimental compounds may be administered just prior to testing.

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